all slots game download main body
Your Location: Home>all slots game download
slot vip singapore
Published: 2025-01-10Source: slot vip singapore

Summary Tips: slot vip singapore is referred to as China News Service Guangxi Channel and China News Service Guangxi Network, which is the first news website established by the central media in Guangxi. 98 slot vip Overall positioning: a comprehensive news website with external propaganda characteristics, the largest external communication platform in Guangxi. slotvip tv Provide services for industry enterprises, welcome to visit slot vip singapore !

slot vip singapore
。98 slot vip
 photograph
slot vip singapore 。98 slot vip photograph
slot vip singapore
slot vip singapore

Evaluating strategic options for iopofosine I 131 a late-stage clinical program with compelling Phase 2 data and a substantial market opportunity Focusing on advancing radiotherapeutic assets including alpha- and Auger-emitting radioconjugates into Phase 1 solid tumor studies FLORHAM PARK, N.J., Dec. 10, 2024 (GLOBE NEWSWIRE) -- Cellectar Biosciences, Inc. (NASDAQ: CLRB), a late-stage clinical biopharmaceutical company focused on the discovery, development and commercialization of drugs for the treatment of cancer, today announces a strategic update on its clinical development programs for its proprietary phospholipid ether drug conjugate platform that delivers a broad array of therapeutic modalities to target cancers. Due to recent communications with the U.S. Food and Drug Administration (FDA, or the Agency) regarding a confirmatory study to support accelerated approval and the regulatory submission for iopofosine I 131, the Company has decided to pursue strategic options for the further development and commercialization of this product candidate. The CLOVER-WaM study was conducted in accordance with earlier FDA communications from an end of Phase 2 meeting and from a meeting in early 2024, during which the Company was informed that positive results for major response rate (MRR) as the primary endpoint could be acceptable to support accelerated approval of iopofosine I 131 as a treatment for Waldenstrom’s macroglobulinemia (WM). Based upon a recent Type-C meeting with the FDA, the Company now believes that a submission seeking accelerated approval would need to be based on the MRR data from CLOVER-WaM and enrollment in a randomized, controlled confirmatory study that is designed to generate data on progression-free survival (PFS). “While iopofosine I 131’s positive WM data along with the high unmet medical need for these patients support further investment, we have determined that such a program may best be brought to market by a larger organization with greater resources. Importantly, partnering or divesting this program supports our commitment to providing this potentially life-saving drug to the patients who need it as quickly as possible,” stated James Caruso, president and CEO of Cellectar. “We believe iopofosine I 131 represents a compelling opportunity as it has shown strong efficacy and good tolerability based on our clinical studies. Moreover, the commercial work we conducted demonstrates iopofosine I 131’s substantial market opportunity based upon the product profile, which includes off-the-shelf global distribution, orphan pricing and existing unmet medical need.” Cellectar remains confident in the potential of its phospholipid ether drug conjugate platform and the targeted radiotherapies in its development pipeline. Iopofosine I 131’s clinical success validates the platform’s ability to target cancers and Cellectar will leverage its experience to focus on the development of its earlier clinical programs. Specifically, Cellectar will focus on those assets it believes have the highest therapeutic potential and opportunity for value creation. As highlighted by recent acquisitions and collaborations within the radiopharmaceutical sector, precision isotopes like alpha- and Auger-emitters have emerged as the leading therapeutics of interest. Consequently, the Company will now focus its resources on targeting solid tumors by advancing CLR 121225, its actinium-225 based program, and CLR 121125, its iodine-125 Auger-emitting program into the clinic. Cellectar expects to file Investigational New Drug applications in the first half of 2025 for both CLR-121225 and CLR-121125, which will allow the initiation of Phase 1 clinical studies in solid tumor cancers. Both programs have demonstrated robust in vivo activity, tolerability, excellent targeting and uptake in preclinical solid tumor models. The Company believes this approach will provide an expedited timeframe to achieve safety and proof-of-concept data in patients. The Company’s strategic reprioritization will impact all departments and result in an immediate reduction in headcount of approximately 60%, which should be complete by the end of the fourth quarter 2024. The Company anticipates that the implementation of the restructuring will extend its cash runway into the third quarter of 2025. “We are being methodical in our efforts to reorganize the company with the goal of conserving cash while maintaining the flexibility to execute immediate priorities and build for long-term growth and value creation. This reorganization is difficult but necessary for the future growth potential of Cellectar,” said Mr. Caruso. “I want to extend my deepest gratitude to our departing employees for their significant contributions to our work and their dedication to making a difference in the lives of patients.” About Cellectar Biosciences, Inc. Cellectar Biosciences is a late-stage clinical biopharmaceutical company focused on the discovery and development of proprietary drugs for the treatment of cancer, independently and through research and development collaborations. The company’s core objective is to leverage its proprietary Phospholipid Drug ConjugateTM (PDC) delivery platform to develop the next-generation of cancer cell-targeting treatments, delivering improved efficacy and better safety as a result of fewer off-target effects. The company’s product pipeline includes lead asset, iopofosine I 131, a small-molecule PDC designed to provide targeted delivery of iodine-131 (radioisotope), CLR 121225, an actinium-225 based program being targeted to several solid tumors with significant unmet need, such as pancreatic cancer, CLR 121125, an iodine-125 Auger-emitting program targeted in other solid tumors, such as triple negative breast, lung and colorectal, proprietary preclinical PDC chemotherapeutic programs and multiple partnered PDC assets. In addition, iopofosine I 131 is under evaluation in Phase 2b studies for relapsed or refractory multiple myeloma (MM) and central nervous system (CNS) lymphoma, alongside the CLOVER-2 Phase 1b study, targeting pediatric patients with high-grade gliomas, for which Cellectar is eligible to receive a Pediatric Review Voucher from the FDA upon approval. The FDA has also granted iopofosine I 131 Orphan Drug and Fast Track Designations for various cancer indications. New data from the CLOVER-WaM Phase 2 clinical trial were recently presented in an oral presentation at the 66th American Society of Hematology Annual Meeting and Exposition (ASH 2024). For more information, please visit www.cellectar.com or join the conversation by liking and following us on the company’s social media channels: Twitter, LinkedIn, and Facebook. Forward-Looking Statement Disclaimer This news release contains forward-looking statements. You can identify these statements by our use of words such as "may," "expect," "believe," "anticipate," "intend," "could," "estimate," "continue," "plans," or their negatives or cognates. These statements are only estimates and predictions and are subject to known and unknown risks and uncertainties that may cause actual future experience and results to differ materially from the statements made. These statements are based on our current beliefs and expectations as to such future outcomes. Drug discovery and development involve a high degree of risk. Factors that might cause such a material difference include, among others, uncertainties related to the ability to raise additional capital, uncertainties related to the disruptions at our sole source supplier of iopofosine, the ability to attract and retain partners for our technologies, the identification of lead compounds, the successful preclinical development thereof, patient enrollment and the completion of clinical studies, the FDA review process and other government regulation, our ability to obtain regulatory exclusivities, the availability of priority review vouchers, our ability to successfully develop and commercialize drug candidates, competition from other pharmaceutical companies, product pricing and third-party reimbursement. A complete description of risks and uncertainties related to our business is contained in our periodic reports filed with the Securities and Exchange Commission including our Form 10-K/A for the year ended December 31, 2023, and our Form 10-Q for the quarter ended September 30, 2024. These forward-looking statements are made only as of the date hereof, and we disclaim any obligation to update any such forward-looking statements. Contacts MEDIA: Christy Maginn Bliss Bio Health 703-297-7194 cmaginn@blissbiohealth.com INVESTORS: Anne Marie Fields Precision AQ 212-362-1200 annemarie.fields@precisionaq.com

France’s president, Emmanuel Macron, has said that he will name a new prime minister “within days” to replace Michel Barnier, who officially resigned on Thursday, a day after opposition lawmakers voted to topple his government. Here are some of the possible candidates: Sébastien Lecornu Sébastien Lecornu defected from the centre-right Les Républicains party and rallied behind Macron’s 2017 presidency, going on to become one of the president’s staunchest allies. He joined Macron’s government alongside Bruno Le Maire, Macron’s long-serving finance minister, and former interior minister Gérald Darmanin who had also both defected from the conservatives. Lecornu, 38, most recently served as defence minister in Barnier’s outgoing government , overseeing increases in defence spending and France’s support of military aid to Ukraine. Investigative news website Mediapart and newspaper Libération reported that Lecornu had dined earlier in the year with Macron’s arch-rival, Marine Le Pen of the far-right National Rally (RN), and they had discussed the war in Ukraine. Lecornu denied the encounter. François Bayrou François Bayrou, 73, is a centrist veteran whose Democratic Movement (MoDem) party has been a part of Macron’s ruling alliance since 2017 . Bayrou, a longtime mayor of the south-western town of Pau who has made his rural roots central to his political identity, decided against running a fourth presidential race in 2017, instead rallying behind Macron. Macron appointed Bayrou as justice minister but he resigned only weeks later amid an investigation into his party’s alleged fraudulent employment of parliamentary assistants. He was cleared of fraud charges this year. Bernard Cazeneuve Bernard Cazeneuve was a senior member of the Socialist Party before he quit in 2022 in anger over the party’s decision to form an electoral pact with the hard-left France Unbowed (LFI). Cazeneuve, 61, served as prime minister during the final months of socialist François Hollande’s presidency . Before that, he was interior minister, in charge of security during the Charlie Hebdo attack and the Islamist militant assault in Paris on 13 November, 2015. The choice of Cazeneuve would be designed to encourage Socialist lawmakers to move away from the alliance with LFI, Greens and Communists and to expand a centrist ruling group. His name had also circulated in the summer as Macron sought a prime minister following an inconclusive snap election that delivered the current fractured parliament. In the end, he was passed over for Barnier. Xavier Bertrand Xavier Bertrand, 59, is a centre-right politician who heads the northern de-industrialised region of Hauts de France, where Macron has sought to develop an ecosystem around electric vehicle batteries. Bertrand served as a minister under the conservative presidencies of Jacques Chirac and Nicolas Sarkozy and took part in the Republicans’ primary contest ahead of the 2022 presidential election. Bertrand, a former insurance salesman once nicknamed “floc floc” for the sound his rubber-soled shoes made on parliament’s stone floor, was also among the names Macron considered in the summer for the role of prime minister. François Baroin Francois Baroin, 59, is a centre-right career politician, whose father was a student friend of the late president Chirac. He served briefly as finance minister, following a stint as budget minister, at the height of Europe’s sovereign debt crisis in 2011-2012. He was named chairman of Barclays France in 2022. Baroin has been mayor of Troyes in Champagne since 1995US News Today Live Updates on December 24, 2024 : Denzel Washington takes the big leap into faith, gets baptized: 'It took a while but I'm here'

Most of us are not professional chefs or caterers or decorators, so the thought of cooking for and entertaining a Thanksgiving crowd can be daunting. That's why we turned to the experts — professional chefs and caterers and interior designers — to discuss some typical Thanksgiving mistakes and how to avoid them. 1. Not prepping "The overriding first mistake people make is they think they have more time than they do," said Bistro to Go Cafe and Catering executive chef Kate Kobylinski. She regularly hosts her extended family of 30 and knows "every single problem." "Food takes longer to cook, the table takes longer to set and houses take longer to clean than you think." Clean your house on Monday. On Wednesday, dice vegetables so they're "food-show ready," as Kobylinski put it. Prepare (but don't cook) your green bean casserole (leaving off garnishes like fried onions) so it can just be popped in the oven and set the dining room table. 2. Not enlisting help Don't feel that you have to do everything yourself. But be as specific as possible when doling out the assignments. "Don't let them make their own decisions!" Kobylinski said emphatically. Thanksgiving is "micromanager's heaven." For example, have someone bring ice on Thanksgiving Day because going out to buy it takes time and ice hogs freezer space. If you don't like making desserts, have someone bring one. If a guest wants to prepare a side dish, great, but decide beforehand what they will bring. Ahead of dinner, interior designer Kacie Cope likes to set out all of her serving platters with Post-it notes attached denoting what will go on them. "You'll be amazed if you have them labeled," she said. "People can help in a jiff." During the evening, Kobylinski gives people assigned jobs, such as serving drinks or taking charge of an after-dinner game. And the chef is forgiving about using premade ingredients, like gravy or cranberry jelly. "There's no right or wrong way to make any of your foods," she said. But you might want to give a homemade touch to prepared ingredients, like adding sauteed onions or celery to prepared gravy. 3. Not defrosting your turkey "Everyone goes into Thanksgiving Day with a half-frozen turkey," said Kobylinski. "And you can't get the bag of giblets out because they're frozen in place." It takes one day for every 4 pounds of turkey meat to defrost in the refrigerator. (No, it is not safe to leave your frozen turkey out on the counter to thaw and breed bacteria.) So if you've got a 20-pound bird, you've got to start thawing on the Saturday before Thanksgiving. However, there are other methods. Kobylinski suggests submerging the bird and running a thin stream of cold water over it. "It doesn't have to be a lot of water." The U.S. Department of Agriculture says there are only three ways to safely thaw food: In the refrigerator, in cold water or in the microwave. To safely thaw turkey in cold water, the USDA says it takes about 30 minutes per pound. Put the turkey in a leak-proof plastic bag to prevent cross-contamination and submerge it. Change the water every 30 minutes, and cook immediately when it's thawed. If opting for your microwave, follow its instructions for thawing and cook immediately. Then, if you're running late and need to speed things up to satisfy the hungry hordes, you can cut the bird in half before cooking (skin side up). This significantly reduces cooking time, requiring about 10 minutes per pound. Kobylinski also recommends resting the turkey on vegetables in the oven to keep the bottom from getting burned. 4. Serving a dry, overcooked turkey Private chef and culinary educator Emily Larsen warns that those plastic thermometers in supermarket turkeys are setting you up for failure. The USDA says that you should cook a turkey until the internal temperature is 165 degrees. Plastic thermometers don't pop out until the breast meat is at about 180 degrees, "when your turkey is completely dry," Larsen said. Plus, people forget that meat continues to cook once it's out of the oven. She recommends taking a bird out of the oven when it is at 155 degrees — she likes to use an inexpensive instant-read folding probe thermometer — and continue to monitor it. (Insert it into the thickest part of the breast, avoiding the bone.) "Ten dollars [for the thermometer] can save your Thanksgiving," she said. Some feel that buying a frozen rather than fresh bird is another no-no, since freezing leaches water out of the turkey. However, if, despite your best efforts, your turkey is lacking moisture, Kobylinski has a fix: Put warm chicken or turkey stock and clarified butter into a mister and spritz sliced turkey with it before serving. "The same with stuffing if it's too dry," she said. 5. Overcomplicating the menu Thanksgiving Day is not the time to try out a completely new recipe. And you don't have to lay out 10 side dishes. In addition to opting for a simple menu, Kobylinski also recommends figuring out how long your items will take to cook and what method of cooking it requires ahead of time. Your turkey will be monopolizing your oven for four hours, so other oven foods should be limited or be easily reheated during the time that the turkey is resting. (As for resting a turkey, the chef puts her turkey on a hot plate with towels over it so "the meat rebinds itself and stabilizes for a smoother cut.") "Stovetop items should be staggered," she said, so you don't have a frying pan and three pots all going at once. As a sample menu, she suggests you might have one baked potato dish and one mashed. And for vegetables, one baked dish and one that is blanched or grilled. 6. Overcomplicating the decorating Interior designers advise against going too crazy with holiday-specific décor. "There's a lot that's being sold to us that we feel like we need," said Pittsburgh interior designer Amanda Bock. Do you really need a turkey-shaped vase or pilgrim figurines? "They're out for two weeks, and then you have to figure out where to store them," agreed Cope. "It takes an already busy season and makes it stressful in an unnecessary way." Cope says you can take things that are already part of your menu and use them as décor — a bowl of nuts or cranberries, or even removing the label from a cranberry sauce tin and repurposing it as a vase for flowers and fall leaves. Bock adds that dining room table décor should be kept to a minimum, since you'll need space for your food. You don't have to have "big chargers and five plates and three different glasses, plus all of your Thanksgiving food on the table," Bock said. If you do have flowers or a centerpiece in the middle of the table, keep it low, Cope advised. "That way, you can actually see the person who's across the table from you." Tableware and tablecloths might be in fall colors, so they can be repurposed throughout the season. Water glasses or wine goblets could be amber-toned, Bock suggests. 7. Inhibiting the party flow Well in advance of your guests' arrival, think critically about the setup of your home. Don't be afraid to rearrange your furniture so your guests move to different areas and don't all congregate in your kitchen. "You want to make sure that there are areas where people can sit and chat, watch the parade or just hang out together," Bock said. Set up a drinks station and an hors d'oeuvres station in different parts of the house, Bock suggests. Though, she admits, "I can't do that in my house because my dogs would just gobble up the hors d'oeuvres." She suggests repurposing a kitchen nook for kid seating, or as a serving area. Kobylinski might set up a half-built puzzle in a side room. She even puts out winter jackets and boots for "the gentlemen" for the moment when she urges them to go out on the porch to smoke cigars and drink brandy so they won't be underfoot. 8. Forgetting to set the mood As a finishing touch, don't neglect to set the mood by using lamps around the room instead of harsh overhead lights. Putting out tapers or tea candles establishes an intimate feeling. "That just leans into the cozy fall vibe," Cope said of low lighting. But don't use scented candles, Bock warns. Or a smelly flower arrangement. "That can overwhelm you when you're eating," Bock said. Putting on a favorite music playlist can set the mood and take away self-consciousness, especially early in the evening. The most important thing on Thanksgiving is simply for everyone to enjoy each other's company. A little advance preparation can help you, the host, stay relaxed throughout the evening so you can interact with your guests. As Bock advised, "Keep it simple for Thanksgiving." Let friendship and fellowship be the stars of the show. The 98th Macy's Thanksgiving Day Parade coverage is slated from 8:30 a.m. to 12 p.m. EST Thursday, Nov. 28. This year's event will feature 28 clown crews, 26 floats, 16 giant balloons, 11 marching bands, five performance groups, three "baloonicles"—cold-air inflatables driven down the parade route, and numerous performers. Stacker curated a selection of photographs from the past century of the Macy's Thanksgiving Day Parade to help illustrate the history of the iconic event. The parade in New York City, presented by department store chain Macy's, was first held in 1924 under the heading "Macy's Christmas Parade" to promote holiday sales and spotlight the newly expanded and, at the time, largest in the world Herald Square store in Manhattan. The success of the event led organizers to turn the spectacle into an annual tradition. Each year, the parade ends outside the same Herald Square Macy's location. The event has been televised nationally since 1953 on NBC. The parade at first featured Central Park Zoo animals escorted by Macy's employees and professional entertainers for 6 miles from 145th Street in north Manhattan's Harlem to Macy's. A quarter of a million onlookers lined the streets. Real animals were replaced with balloons in 1927; that same year, the name of the event was changed to Macy's Thanksgiving Day Parade. The longest-running parade float is the event's unofficial mascot, Tom Turkey. Tom features moving wings, head, and eyes and usually functions as the lead float in the parade. Bringing up the caboose in virtually all the parades is Santa Claus who ushers in the holiday shopping season with his arrival at Macy's Herald Square. The parade offers a glimpse into pop culture of the time, from beloved children's entertainment to hit Broadway shows and musical acts. The Radio City Rockettes, formed in 1925, have performed in the parade annually since 1957. In 1933, the outside temperature was 69 degrees F, the warmest it's been; 2018 was the coldest day in parade history at 19 degrees F. In 2022, for the first time, the event featured a trio of women hosts. Today, more than 44 million people tune in to watch the parade. Keep reading to learn more about the parade's history and see some iconic shots of the event. You may also like: Game on: The booming growth of online gaming In Macy's first Thanksgiving parade, Santa Claus sat atop a float pulled by a team of horses down Broadway. That year floats, bands, and Central Park Zoo animals were featured in the procession. At the parade's end, Santa Claus was crowned "King of the Kiddies" on Macy's balcony at the 34th Street entrance. Macy's quickly announced the parade would be an annual event. The large balloons that replaced live zoo animals in 1927 were filled with regular air and had no release valves—they were simply let go to pop in the air following the parade. 1928 marked the first year of Macy's inflating balloons with helium to allow them to float. They were also outfitted with valves so the helium could gradually escape rather than waiting for the balloon to inevitably pop, and featured a return address so anyone who found them could return them and receive a reward. In this photo from 1928, a 35-foot fish and 60-foot-long tiger were featured prominently in the parade. A $100 prize was offered for each balloon recovered after its release. The Thanksgiving parade enjoyed rapid growth throughout the 1930s, with more than 1 million revelors lining the parade route in 1933. In this 1931 photo, a giant hippopotamus balloon makes its way down Broadway. A blue hippo balloon—possibly this one—released after the parade was still at large several days later, thought to be somewhere over the Atlantic Ocean. In this image, the Felix the Cat balloon is led down Broadway by its four handlers tailed by Terrible Turk and Willie Red Bird. The original Felix the Cat character balloon made its parade debut in 1927, but was destroyed after its post-parade release by a high tension wire in 1931. The Terrible Turk also was destroyed the same year by an electric sign. In 1932, Macy's Tom Cat balloon got stuck in the propeller of a plane when the aviator flying the plane tried recovering the balloon for a reward. While the plane eventually landed safely, that event marked the final year of releasing balloons after the parades and offering prizes for their return to Macy's. Pinnochio, Tin Man, and Uncle Sam make their way along the parade route in 1939. Mickey Mouse made his debut five years earlier with a balloon designed in part by Walt Disney; Mickey's handlers were also dressed as mice. New iterations of Mickey appeared over the next 70 years as the character evolved. The Macy's Thanksgiving Day Parade was canceled from 1942-1944 because of supply shortages during World War II, namely helium and rubber. Festivities returned in 1945. The Christmas classic "Miracle on 34th Street" was released in 1947 and prominently features actual footage from the 1946 parade. 1948 marked the parade's first network television broadcast. You may also like: Legendary interior designers from every decade of the 20th century Macy's original character The Giant Spaceman made his debut in 1952's parade, measuring 70 feet long and 40 feet wide and weighing 600 pounds. More than 25 gallons of paint went into painting the astronaut. An estimated 2.25 million people lined the streets for the festivities that year. Throngs of onlookers pack the sidewalks in Manhattan's Times Square during this 1955 parade. Mighty Mouse, an animated superhero created by Terrytoons, is seen in the back left of the photo. Mighty Mouse made his debut in the Thanksgiving Day parade in 1951; he appeared in 80 short films between 1942-1961. Popeye makes his way through Times Square in the 1959 parade. A year earlier, another helium shortage meant balloons were inflated with air and hung from construction cranes to make their way through the parade route. Also in 1958, the first celebrity performances were added with the Benny Goodman sextet. Live music proved a challenge technically and logistically. The parade was transitioning to the now-familiar lip syncing by 1964. The iconic peacock float makes its debut in this photo of the 1961 Macy's Thanksgiving Day Parade. That same year, Miss Teenage America Diane Lynn Cox appeared in princess attire sharing a float with "Prince Charming" actor Troy Donahue. You may also like: Baltimore buried its urban streams—now an artist is bringing one back Teen performers appear in classic roller skates in this image from the 1961 Macy's Thanksgiving Day Parade. The sign above the skaters reads "Macy's presents A Fantasy of Christmas in New York." This 1961 photo shows shoulder-to-shoulder parade onlookers at the Macy's Thanksgiving Day Parade. The year marks the first balloon featuring Bullwinkle Moose and the first year for floats with Pinocchio, The Racetrack Grandstand, Cinderella, Peacock, Ferris Wheel, Brigadoon, Meet the Mets, and Santa's Sleigh. Several years later, in 1968, Macy's creative team figured out how to design floats up to 40 feet tall and 28 feet wide that could fold into 12.5-by-8-foot boxes for strategic transportation from New Jersey to Manhattan via the Lincoln Tunnel. A Bullwinkle Moose balloon floats down Broadway in this 1972 photograph of the parade. The 46th annual parade featured five firsts for floats: Alphabet Blocks, Snow Mountain, Windmill, Curious George, and Santa's Holiday Home. A solo tortoise float makes its way down the street near Columbus Circle in this 1974 parade photo. Not pictured is the accompanying hare. This marked the seventh appearance of the duo. A giant inflatable balloon of Kermit the Frog makes its way down the 1982 parade route in this photo. The parade marked Kermit's sixth appearance. First-time balloons included Olive Oyl and Woody Woodpecker. You may also like: Far from making their last calls, LGBTQ+ bars evolve to imagine a new world Woody Woodpecker greets the crowd as he floats past One Times Square during the 63rd annual Macy's Thanksgiving Day Parade in 1989. In the coming years, safety concerns troubled '90s-era parades—namely the wind. Strong gusts in 1993 pushed a Sonic the Hedgehog balloon into a Columbus Circle lamppost that broke and hurt a child and off-duty police officer. Four years later, intense winds caused a Cat in the Hat balloon to hit a lamppost, hurling debris into the air that fractured the skull of a spectator who spent 24 days in a coma. The incident, among others, led then-New York City Mayor Rudy Giuliani to form a task force. The Soaring Spirit Canoe float, pictured here in 1995, made its debut in the parade in 1986. Popular '90s balloons included Bart Simpson, Cat in the Hat, and The Rugrats. New York City first responders carry two American flags during the Nov. 22, 2001, 75th Anniversary of Macy's Thanksgiving Day Parade, which was also held on the heels of 9/11. They honored those killed in the Sept. 11 terrorist attacks that year. New Yorkers crowded the streets to watch the parade, which featured 15 giant balloons and marching bands that all added an air of patriotism to the event. Dora the Explorer makes her balloon debut in this 2005 photo. That same year, the M&M 's chocolate candies balloon collided with a streetlight in Times Square, and debris from it injured two siblings. A woman dressed in an elf costume sprinkles spectators with confetti in Times Square during Macy's 85th Thanksgiving Day parade on Nov. 24, 2011. Sonic the Hedgehog and Julius the sock monkey, which was created by Paul Frank, made their balloon entrances that year. You may also like: 5 tips for making your next event more affordable In this 2016 photo, spectators like this one recorded videos of the parade on their phones. More than 24 million people were estimated to have streamed the parade that year on TV. Santa Claus celebrates at the 97th annual Macy's Thanksgiving Day Parade in this photo from Nov. 23, 2023. First-time giant balloons included Beagle Scout Snoopy, Leo (Netflix), Monkey D. Luffy, Po from "Kung Fu Panda," and The Pillsbury Doughboy. Copy editing by Lois Hince. You may also like: From the Roman Empire to your therapist's office: The history of the chaise lounge The 23rd annual Macy's Thanksgiving Day Parade was held Nov. 24, 1949. In this photo, a teddy bear makes its way through Times Square. This parade marked the second appearance for the bear. Other balloons made their debut: Freida the Dachshund, Howdy Doody on the Flying Trapeze, and Macy's Hobo Clown. Snoopy and Woodstock made their way along the 89th annual Macy's Thanksgiving Day Parade route Nov. 26, 2015. To date, Snoopy boasts the most years flown as a character balloon in the event. The Pikachu balloon floats down Central Park West for its fourth time during the 91st annual Macy's Thanksgiving Day Parade in 2017. That year's lineup featured 1,100 cheerleaders and dancers, more than 1,000 clowns, 28 legacy balloons, 26 floats, 17 giant helium balloons, 12 marching bands, and six performance groups. Performers in this photo prepare at the 94th annual Macy's Thanksgiving Day Parade on Nov. 26, 2020. The event was one of few public occasions to be kept on schedule during the COVID-19 pandemic, albeit in a tempered manner. Much of the performances were pre-taped and the parade route was massively reduced. Participants wore masks and balloon handlers were cut by nearly 90%. Make your house a home For the holidays: Get inspiring home and gift ideas – sign up now!

By Kemberley Washington, CPA, Bankrate.com (TNS) As the end of the year approaches, now’s the time to start preparing for filing your 2024 tax return in 2025. When it comes to tax strategies, generally Dec. 31 is the deadline to make changes that might lower your tax bill. One major exception is the deadline for contributing to a Roth or traditional IRA : You have until April 15, 2025, to make a contribution to a Roth or traditional IRA for tax year 2024. If you qualify for deductible IRA contributions , then a contribution to your traditional IRA can reduce your taxable income for 2024. Here are tips and strategies to prepare now for the 2025 tax-filing deadline. 1. Decide who will prepare your taxes If you had significant changes in your life in 2024 — maybe you got married or divorced, started your own business, or had to claim unemployment benefits — your taxes may be more complicated. As a result, you might need to hire a certified public accountant (CPA), enrolled agent (EA) or other tax professional to prepare and file your taxes. If you decide to hire someone, it’s best to start planning for that sooner rather than later. Waiting until the calendar flips to April could cost you. The average fee for a professional to prepare and file a simple Form 1040 tax return, with no itemized deductions, is about $220, according to a survey by the National Society of Accountants in 2020-2021, the most recent data available. But that amount rises quickly for more complex returns, and varies depending on where you live. For example, a Form 1040 with itemized deductions costs an average of $432 in states on the Pacific Coast, compared with $285 in New England. No matter where you live, prices usually rise as the tax deadline approaches, so it’s smart to start searching for a tax pro soon. 2. Find ways to file for free If you’re uncomfortable doing your taxes on your own and can’t afford a CPA, enrolled agent or other tax pro, or to pay for tax software , there are free options to consider. The IRS currently offers three ways to prepare your taxes for free: •With the IRS Free File program, the IRS partners with for-profit tax-software companies that offer free tax-prep software to eligible taxpayers so they can file their federal tax returns for free. Some taxpayers may also qualify for a free state tax filing, depending on the software provider. In January, the IRS will announce the income limit to qualify for the program for the 2025 tax season (for filing 2024 tax returns). For the 2024 tax season (2023 tax returns), taxpayers’ adjusted gross income (AGI) couldn’t exceed $79,000. •The IRS also offers its Direct File program, a free tool that allows you to file your federal income tax return directly with the IRS at no cost. The program supports simple tax returns and is available only in certain states. Check to see if you qualify here. •Another free-filing option is the Volunteer Income Tax Assistance (VITA) program. IRS-certified volunteers offer free basic tax preparation in person to people who earn less than $67,000 a year, are disabled or whose English is limited. The IRS has an online location tool for hundreds of free tax preparation sites in the U.S. (the locator tool is updated from February through April). Some VITA sites also offer online tax-prep assistance. 3. Create an online IRS account Now is a good time to create an IRS online account. If you want to see your Form 1040 from last year, or you’re missing a prior year Form W-2 or mortgage interest statement, you can find your documents using this free tax tool. Another benefit of creating an IRS online account is that it allows you to quickly obtain your prior year’s tax information without sitting on the phone for hours with an IRS representative, says Carl Johnson, a certified public accountant in New Orleans. An IRS online account also lets you view your account balance and payment history for each year. You can also create a payment plan to settle your federal income tax debt within minutes. 4. Take your required minimum distributions (RMDs) If you’re 73 years old and have enjoyed watching your 401(k) or IRA grow tax-free without touching it, remember that the IRS is going to want its share each year. That means you’ll have to make withdrawals — and pay income tax. If you turned 73 in 2024, plan to take your required minimum distribution (RMD) at the latest by April 1, 2025. Read this IRS bulletin for more information. The amount of your RMDs is based on your age and the year-end values of your retirement accounts. 5. Think long-term: Consider converting an IRA to a Roth A Roth IRA has two big tax advantages over a traditional IRA : Qualified withdrawals are not considered income for federal (and usually state) tax purposes, and you don’t have to take distributions from a Roth every year once you reach age 73. Converting a traditional IRA to a Roth IRA may save you money in the long run. Just know that when you convert an IRA to a Roth, it’s considered taxable income, which will raise your tax bill for that year. Generally, it’s best to convert to a Roth IRA when you’re in a low-income year. 6. Protect yourself from tax scams and fraud As tax season approaches, many people start receiving phone calls, emails and texts from entities claiming to be the IRS. Be wary, and understand that these are scams. Typically, the IRS will mail you a notice before using any other method of communication to notify you concerning issues with your tax return. The IRS won’t reach out via social media or text messaging. Relatedly, the IRS warns taxpayers to be careful when choosing a tax preparer. Taking time to vet your tax preparer is crucial to protect yourself from tax scams and fraud. Before hiring a tax professional, search that person’s name in the IRS database of federal tax return preparers to avoid dishonest “professionals.” “Taxpayers should check the tax professional’s credentials,” Johnson says. Tax pros without credentials “may take questionable positions without any degree of scrutiny or fear of losing their access to the profession,” Johnson says. 7. Don’t ignore the IRS Taxpayers who don’t file a tax return and owe a tax bill, or who file but don’t pay their tax bill on time, risk severe penalties. The IRS can even seize assets if necessary. Respond quickly if the IRS has been sending you letters because it found an error on your return or claims you owe back taxes. Typically, the IRS will send you a notice if you have a balance due, changes were made to your tax return, or the agency needs additional information. “If you ignore a collection letter from the IRS, you may face wage garnishments, liens, bank levies, and other adverse action. And in some cases, the amount due may increase for failure to respond,” Johnson says. Keep in mind the IRS does offer installment plans and other payment plans. Make copies of your correspondence and use only the U.S. Postal Service, the postmark from which is your proof of timeliness when responding. But whatever you do, don’t ignore the IRS because this may cause more issues in the future. ©2024 Bankrate.com. Distributed by Tribune Content Agency, LLC.

Reading Ranking

Hot pictures

  • 88 jili casino
  • mpo99bet
  • winph4
  • the wild ace

The information published on this website does not represent the views of this website. The use of articles on this website requires written authorization.
Reprinting, excerpting, copying and mirroring are prohibited without authorization. Violators will be held accountable according to law.