DENVER--(BUSINESS WIRE)--Dec 18, 2024-- Colorado BioScience Association (CBSA) announces the state’s life sciences ecosystem raised $2.15 billion in 2024, a 46% increase compared to 2023. Colorado, recognized as the Hub for Health Impact , has attracted close to $12 billion for life sciences research and development during the last eight years from public and private sources, as well as federal, state, and foundation grants. Colorado’s life sciences companies and organizations demonstrated fundraising strength throughout 2024, surging past $1 billion in the first two quarters of the year, according to CBSA data. The 2024 numbers mark the second time in a four-year period that funding totals have reached $2 billion. During the record fundraising of 2021, fueled by the pandemic, Colorado companies and organizations raised $2.4 billion. “Colorado BioScience Association applauds our ecosystem’s phenomenal fundraising success. Investors know there’s a unique and powerful convergence of world-changing technologies being developed in Colorado, with life sciences playing an interconnected role,” said Elyse Blazevich, President & CEO of Colorado BioScience Association. “Life sciences investors, companies, and talent are seeing and seizing the opportunities in Colorado because of our collaborative community, top-ranked talent, central location, robust infrastructure, reasonable costs, and unmatched quality of life. It’s no surprise Colorado now ranks in the top quintile for life sciences venture capital funding.” Colorado Life Sciences Financings: Eight-Year History Colorado’s life sciences fundraising is approaching close to $12 billion raised in the last eight years. 2024: $2.15B 2023: $1.47B 2022: $1.6B 2021: $2.4B 2020: $1.2B ($2.6B including Invitae acquisition of ArcherDX) 2019: $850M ($12.B including Pfizer acquisition of Array Biopharma) 2018: $1.0B 2017: $1.2B Funding Sources Colorado companies raised $818.5 million in public capital, a 64% increase compared to 2023 through post-IPO equity and debt, $445.0 million through mergers, acquisitions, and partnerships, and $383.0 million in private capital, primarily from venture funding. Private Capital $383.0M Pre-Seed/Seed $23.0M Series A + B $183.4M Series C, D + Later $146.4M Other $30.1M Underscoring the ecosystem’s maturity and growth, several high-profile Colorado companies recently announced clinical milestones, including Edgewise Therapeutics , Enveda , OnKure Therapeutics , and Umoja Biopharma . Federal Grants Federal funding provides critical capital for research and development at private companies and academic and research institutions, with grants from the National Institutes of Health and National Science Foundation totaling $496.6 million. In many cases, the grant dollars are deployed through the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The University of Colorado System, Colorado State University, and National Jewish Health continue to rank as the state’s leading recipients of federal funding for life sciences research and development. State Grants The State of Colorado’s Office of Economic Development and International Trade awarded $5.5 million in Advanced Industries Accelerator Grants to life sciences companies and university researchers in 2024. “Thanks to critical funding from the state’s Advanced Industries Accelerator Grant Program, Colorado companies and researchers are advancing technologies that will revolutionize health and care,” said Blazevich. “CBSA is fighting to preserve this program from projected state budget cuts in 2025, because it saves and changes lives with breakthroughs developed here in Colorado. The program provides significant return on investment to the state, attracting $2.9 billion in follow-on capital for Colorado’s advanced industries since 2016 and creating more than 5,000 jobs.” Colorado’s life sciences community makes a vital contribution to health innovation for patients and the state’s economy, providing mission-driven, high-paying jobs to more than 41,000 Coloradans, according to new data from BIO . The $52.9 billion in economic impact by Colorado’s life sciences ecosystem generates tax dollars, funds critical infrastructure and education, and supports families and communities. CBSA compiles and analyzes annual life sciences financings using publicly available sources, including company news releases, media reports, SEC filings, federal and state databases, as well as Crunchbase. Connect with CBSA: Twitter/X , Facebook and LinkedIn About Colorado BioScience Association Colorado BioScience Association (CBSA) creates co-opportunity for the Colorado life sciences community. CBSA champions a collaborative life sciences ecosystem and advocates for a supportive business climate. From concept to commercialization, member companies and organizations drive global health innovations, products, and services that improve and save lives. The association leads Capital and Growth, Education and Networking, Policy and Advocacy, and Workforce Cultivation to make its members stronger, together. Learn more: cobioscience.com View source version on businesswire.com : https://www.businesswire.com/news/home/20241218192950/en/ CONTACT: Media Contact:Sheliah Reynolds Primavera Group for Colorado BioScience Association (720) 289-4739 sheliah@theprimaveragroup.com KEYWORD: COLORADO UNITED STATES NORTH AMERICA INDUSTRY KEYWORD: RESEARCH FINANCE PUBLIC POLICY/GOVERNMENT CLINICAL TRIALS PROFESSIONAL SERVICES BIOTECHNOLOGY HEALTH STATE/LOCAL SCIENCE SOURCE: Colorado BioScience Association Copyright Business Wire 2024. PUB: 12/18/2024 04:41 PM/DISC: 12/18/2024 04:40 PM http://www.businesswire.com/news/home/20241218192950/en Copyright Business Wire 2024.does mgm have casinos in macau 。

US budget airlines are struggling. Will pursuing premium passengers solve their problems? DALLAS (AP) — Delta and United Airlines have become the most profitable U.S. airlines by targeting premium customers while also winning a significant share of budget travelers. That is squeezing smaller low-fare carriers like Spirit Airlines, which filed for bankruptcy protection on Monday. Some travel industry experts think Spirit’s troubles indicate less-wealthy passengers will have fewer choices and higher prices. Other discount airlines are on better financial footing but also are lagging far behind the full-service airlines when it comes to recovering from the COVID-19 pandemic. Most industry experts think Frontier and other so-called ultra-low-cost carriers will fill the vacuum if Spirit shrinks, and that there's still plenty of competition to prevent prices from spiking. Bitcoin ticks closer to $100,000 in extended surge following US elections NEW YORK (AP) — Bitcoin is jumping again, setting another new high above $99,000. The cryptocurrency has been shattering records almost daily since the U.S. presidential election, and has rocketed more than 40% higher in just two weeks. It's now at the doorstep of $100,000. Cryptocurrencies and related investments like crypto exchange-traded funds have rallied because the incoming Trump administration is expected to be more “crypto-friendly.” Still, as with everything in the volatile cryptoverse, the future is hard to predict. And while some are bullish, other experts continue to warn of investment risks. Supreme Court steps into fight over FCC's $8 billion subsidies for internet and phone services WASHINGTON (AP) — The Supreme Court has stepped into a major legal fight over the $8 billion a year the federal government spends to subsidize phone and internet services in schools, libraries and rural areas, in a new test of federal regulatory power. The justices on Friday agreed to review an appellate ruling that struck down as unconstitutional the Universal Service Fund. The Federal Communications Commission collects money from telecommunications providers, who then pass the cost on to their customers. The Biden administration appealed the lower court ruling, but the case probably won’t be argued until late March. At that point, the Trump administration will be in place and it is not clear whether it will take a different view of the issue. Stock market today: Wall Street gains ground as it heads for a winning week Stocks gained ground on Wall Street, keeping the market on track for its fifth gain in a row. The S&P 500 was up 0.2% in afternoon trading Friday. The Dow Jones Industrial Average climbed 333 points and the Nasdaq composite was essentially flat. Retailers had some of the biggest gains. Gap soared after reporting quarterly results that easily beat analysts' estimates. EchoStar fell after DirecTV called of its purchase of that company's Dish Network unit. European markets closed mostly higher and Asian markets ended mixed. Treasury yields held relatively steady in the bond market. Crude oil prices gained ground. Australia rejects Elon Musk's claim that it plans to control access to the internet MELBOURNE, Australia (AP) — An Australian Cabinet minister has rejected X Corp. owner Elon Musk’s allegation that the government intends to control all Australians' access to the internet through legislation that would ban young children from social media. Treasurer Jim Chalmers said on Friday that Musk’s criticism was “unsurprising” after the government introduced legislation to Parliament that would fine platforms including X up to $133 million for allowing children under 16 to hold social media accounts. The spat continues months of open hostility between the Australian government and the tech billionaire over regulators’ efforts to reduce public harm from social media. Parliament could pass the legislation as soon as next week. Oil company Phillips 66 faces federal charges related to alleged Clean Water Act violations LOS ANGELES (AP) — Oil company Phillips 66 has been federally indicted in connection with alleged violations of the Clean Water Act in California. The Texas-based company is accused of discharging hundreds of thousands of gallons of industrial wastewater containing excessive amounts of oil and grease. The U.S. Department of Justice announced the indictment on Thursday. Phillips is charged with two counts of negligently violating the Clean Water Act and four counts of knowingly violating the Clean Water Act. An arraignment date has not been set. A spokesperson for the company said it was cooperating with prosecutors. US regulators seek to break up Google, forcing Chrome sale as part of monopoly punishment U.S. regulators want a federal judge to break up Google to prevent the company from continuing to squash competition through its dominant search engine after a court found it had maintained an abusive monopoly over the past decade. The proposed breakup floated in a 23-page document filed late Wednesday by the U.S. Justice Department calls for Google to sell its industry-leading Chrome web browser and impose restrictions designed to prevent Android from favoring its search engine. Regulators also want to ban Google from forging multibillion-dollar deals to lock in its dominant search engine as the default option on Apple’s iPhone and other devices. What you need to know about the proposed measures designed to curb Google's search monopoly U.S. regulators are proposing aggressive measures to restore competition to the online search market after a federal judge ruled that Google maintained an illegal monopoly. The sweeping set of recommendations filed late Wednesday could radically alter Google’s business. Regulators want Google to sell off its industry-leading Chrome web browser. They outlined a range of behavioral measures such as prohibiting Google from using search results to favor its own services such as YouTube, and forcing it to license search index data to its rivals. They're not going as far as to demand Google spin off Android, but are leaving that door open if the remedies don't work. Apple and Google face UK investigation into mobile browser dominance LONDON (AP) — A British watchdog says Apple and Google aren't giving consumers a genuine choice of mobile web browsers. The watchdog's report Friday recommends they face an investigation under new U.K. digital rules taking effect next year. The Competition and Markets Authority took aim at Apple, saying the iPhone maker’s tactics hold back innovation by stopping rivals from giving users new features like faster webpage loading. The CMA’s report also found that Apple and Google manipulate the choices given to mobile phone users to make their own browsers “the clearest or easiest option.” Apple said it disagreed with the findings. Atlantic City casino earnings fall nearly 14% in 3rd quarter ATLANTIC CITY, N.J. (AP) — Atlantic City’s casinos saw their operating profits decline by nearly 14% in the third quarter of this year. New Jersey gambling regulators say the nine casinos had a collective gross operating profit of $236.5 million in the third quarter. That was down 13.8% from the third quarter of 2023. Every casino was profitable, but only two — Caesars and Hard Rock — saw their profits increase in the third quarter compared with a year ago. Hard Rock had the highest average hotel occupancy at over 95%, and Ocean had the highest average hotel room price at $335.By REBECCA SANTANA WASHINGTON (AP) — President-elect Donald Trump has promised to end birthright citizenship as soon as he gets into office to make good on campaign promises aiming to restrict immigration and redefining what it means to be American. But any efforts to halt the policy would face steep legal hurdles. Birthright citizenship means anyone born in the United States automatically becomes an American citizen. It’s been in place for decades and applies to children born to someone in the country illegally or in the U.S. on a tourist or student visa who plans to return to their home country. It’s not the practice of every country, and Trump and his supporters have argued that the system is being abused and that there should be tougher standards for becoming an American citizen. But others say this is a right enshrined in the 14th Amendment to the Constitution, it would be extremely difficult to overturn and even if it’s possible, it’s a bad idea. Here’s a look at birthright citizenship, what Trump has said about it and the prospects for ending it: During an interview Sunday on NBC’s “Meet the Press” Trump said he “absolutely” planned to halt birthright citizenship once in office. “We’re going to end that because it’s ridiculous,” he said. Trump and other opponents of birthright citizenship have argued that it creates an incentive for people to come to the U.S. illegally or take part in “birth tourism,” in which pregnant women enter the U.S. specifically to give birth so their children can have citizenship before returning to their home countries. “Simply crossing the border and having a child should not entitle anyone to citizenship,” said Eric Ruark, director of research for NumbersUSA, which argues for reducing immigration. The organization supports changes that would require at least one parent to be a permanent legal resident or a U.S. citizen for their children to automatically get citizenship. Others have argued that ending birthright citizenship would profoundly damage the country. “One of our big benefits is that people born here are citizens, are not an illegal underclass. There’s better assimilation and integration of immigrants and their children because of birthright citizenship,” said Alex Nowrasteh, vice president for economic and social policy studies at the pro-immigration Cato Institute. In 2019, the Migration Policy Institute estimated that 5.5 million children under age 18 lived with at least one parent in the country illegally in 2019, representing 7% of the U.S. child population. The vast majority of those children were U.S. citizens. The nonpartisan think tank said during Trump’s campaign for president in 2015 that the number of people in the country illegally would “balloon” if birthright citizenship were repealed, creating “a self-perpetuating class that would be excluded from social membership for generations.” In the aftermath of the Civil War, Congress ratified the 14th Amendment in July 1868. That amendment assured citizenship for all, including Black people. “All persons born or naturalized in the United States and subject to the jurisdiction thereof, are citizens of the United States and of the State wherein they reside,” the 14th Amendment says. “No State shall make or enforce any law which shall abridge the privileges or immunities of citizens of the United States.” But the 14th Amendment didn’t always translate to everyone being afforded birthright citizenship. For example, it wasn’t until 1924 that Congress finally granted citizenship to all Native Americans born in the U.S. A key case in the history of birthright citizenship came in 1898, when the U.S. Supreme Court ruled that Wong Kim Ark, born in San Francisco to Chinese immigrants, was a U.S. citizen because he was born in the states. The federal government had tried to deny him reentry into the county after a trip abroad on grounds he wasn’t a citizen under the Chinese Exclusion Act. But some have argued that the 1898 case clearly applied to children born of parents who are both legal immigrants to America but that it’s less clear whether it applies to children born to parents without legal status or, for example, who come for a short-term like a tourist visa. “That is the leading case on this. In fact, it’s the only case on this,” said Andrew Arthur, a fellow at the Center for Immigration Studies, which supports immigration restrictions. “It’s a lot more of an open legal question than most people think.” Some proponents of immigration restrictions have argued the words “subject to the jurisdiction thereof” in the 14th Amendment allows the U.S. to deny citizenship to babies born to those in the country illegally. Trump himself used that language in his 2023 announcement that he would aim to end birthright citizenship if reelected. Trump wasn’t clear in his Sunday interview how he aims to end birthright citizenship. Asked how he could get around the 14th Amendment with an executive action, Trump said: “Well, we’re going to have to get it changed. We’ll maybe have to go back to the people. But we have to end it.” Pressed further on whether he’d use an executive order, Trump said “if we can, through executive action.” He gave a lot more details in a 2023 post on his campaign website . In it, he said he would issue an executive order the first day of his presidency, making it clear that federal agencies “require that at least one parent be a U.S. citizen or lawful permanent resident for their future children to become automatic U.S. citizens.” Related Articles National Politics | Trump has flip-flopped on abortion policy. His appointees may offer clues to what happens next National Politics | In promising to shake up Washington, Trump is in a class of his own National Politics | Election Day has long passed. In some states, legislatures are working to undermine the results National Politics | Trump taps his attorney Alina Habba to serve as counselor to the president National Politics | US announces nearly $1 billion more in longer-term weapons support for Ukraine Trump wrote that the executive order would make clear that children of people in the U.S. illegally “should not be issued passports, Social Security numbers, or be eligible for certain taxpayer funded welfare benefits.” This would almost certainly end up in litigation. Nowrasteh from the Cato Institute said the law is clear that birthright citizenship can’t be ended by executive order but that Trump may be inclined to take a shot anyway through the courts. “I don’t take his statements very seriously. He has been saying things like this for almost a decade,” Nowrasteh said. “He didn’t do anything to further this agenda when he was president before. The law and judges are near uniformly opposed to his legal theory that the children of illegal immigrants born in the United States are not citizens.” Trump could steer Congress to pass a law to end birthright citizenship but would still face a legal challenge that it violates the Constitution. Associated Press reporter Elliot Spagat in San Diego contributed to this report.

A recent bushfire in Kadnook, western Victoria, which destroyed at least one property and burned more than 1,000 hectares of land, is being investigated due to . or signup to continue reading This is not an isolated example. About 28% of bushfires in south-east Australia are . The figure rises to 40% if we're only talking about fires with a known cause. These figures are consistent with and tell us preventing arson and unsafe fire behaviour alone could significantly reduce the number of bushfires. Despite this, prevention of deliberately lit bushfires is mostly absent from emergency, public health and climate action plans. Deliberately lit bushfires can spread rapidly and have devastating consequences. They often occur close to populated places, where there are both dense vegetation and flammable structures. We see a peak in bushfires during summer when hot temperatures, low rainfall, and dry conditions make fire a more potent threat. Climate change, land management practices, and increased interaction between people and rural areas increase our vulnerability to fire and the risks associated with deliberate fires. The royal commission into Victoria's devastating Black Saturday fires in 2009 173 people died and an additional . The commission concluded at least three of the 15 fires that caused (or had the potential to cause) the greatest harm were deliberately lit. The commission concluded we need to better understand arson. It recommended research to improve how best to prevent arson and how to detect who's at risk of offending. Nearly 15 years on from Black Saturday, these recommendations have not been implemented. There is also very limited evidence globally about how to prevent both bushfire arson and deliberately lit fires more broadly (for instance, fires set to structures or vehicles). We know little about the characteristics and psychology of people who light bushfires or how to intervene to prevent these fires. The little research we have suggests there is no one "profile" or "mindset" associated with deliberately lighting bushfires. But there are some risk factors or we see more commonly in people who light them. These include: However, most people with these vulnerabilities will never light a fire. Research shows in people who set fires (including schizophrenia, mood and anxiety disorders, personality dysfunction, and substance use disorders). However, mental health symptoms are . Instead, they appear to worsen existing vulnerabilities. There are many, complex reasons why people light fires. Commonly reported drivers : relieving boredom or creating excitement, gaining positive recognition for putting out a fire (they want to be seen as a hero), as a cry for help, or because they're angry. However, not everyone who lights a fire intends to cause serious damage or harm. In some cases, people may not be aware of the possible consequences of lighting a fire or that the fire may spread into a bushfire. Knowing these kinds of facts about people who light bushfires is important. However, they don't help us prevent people from lighting fires in the first place. This is because authorities don't always know who sets the fires. First, we can learn more about why people set fires more generally, particularly those who do not attract attention from authorities. Research in the , and has started to investigate those who set fires but don't attract police attention. The aim is to identify ways to prevent people lighting fires in the first place, and support them so they don't light more. There is almost no research in Australia or internationally into the effects of community awareness, and prevention campaigns or targeted strategies to prevent firesetting, including bushfire arson, in higher risk groups. We know slightly more about interventions to reduce repeat firesetting. delivered by fire and rescue services show some promise as an early intervention for children and adolescents who have already set a fire, particularly those motivated by curiosity, experimentation, or who are not aware of the consequences. There is also some evidence suggesting can be effective in reducing vulnerabilities associated with adult firesetting. Forensic or clinical psychologists typically deliver a combination of cognitive behavioural therapy (a type of talking therapy), skills building (such as building coping skills, emotion and impulse control, and reducing their interest in fire), and fire safety education. However, both in Australia and internationally. Interventions that are available are also not always tailored to people with , such as those with significant emotional or behavioural problems or mental health needs. We also don't know if these interventions lead to a long-term change in behaviour. The continued and escalating effects of climate change makes it more urgent than ever to address the problem of . Failing to address deliberate firesetting will have significant long-term consequences for public health, human life and the environment. But until funding is available for Australian arson research, identifying and helping people who are more likely to set fires will continue to be based on guesswork rather than evidence. As we enter another summer of high fire danger, our failure to fund arson research should be at the forefront of everyone's minds. , Senior Lecturer in Forensic Psychology, and , Professor of Clinical and Forensic Psychology, This article is republished from under a Creative Commons license. Read the . 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Confront the common cold with a beloved seasonal stapleDecember 12 - Colorado is gearing up for the rugged Big 12 schedule, but first the Buffaloes wrap up their nonconference slate with two more games, starting Friday night when they host South Dakota State in Boulder, Colo. Colorado (7-2) has won two straight after competing in the Maui Invitational, most recently a 72-55 win over in-state rival Colorado State. Now the focus turns to South Dakota State and shoring up issues before conference play. "Defensively, we're understanding what our jobs are. Now, we're not where we need to be for sure," coach Tad Boyle said. "But we're making strides in that area. And I think the guys are getting used to playing with each other, understanding each other." The Buffaloes lost a lot of talent from last year's NCAA Tournament team but boast some quality players. Andrej Jakimovski (13.0 points per game), Julian Hammond III (12.3 ppg) and Elijah Moore (12.0 ppg) lead the team in scoring. Sophomore big man Bangot Dak has shown he can be a force after scoring a career-high 16 points in the win over Colorado State. The Jackrabbits (8-4) are coming off a 77-63 loss at Nevada on Wednesday night and complete a two-game trip in Boulder. South Dakota State is led by senior center Oscar Cluff, who tops the team in scoring (17.3 points) and rebounding (11.0) but had a subpar night against Nevada when he scored a season-low six points while battling an ankle injury. "I wish he was feeling a little better," coach Eric Henderson said of Cluff. "He's going to be fine, but he's still nursing that ankle a little bit." Freshman Joe Sayler is second on the team in scoring at 12.8 ppg and has reached double figures in each of the last three games. Sophomore Kalen Garry is third on the Jackrabbits in scoring at 9.6 per contest, an average that has been hurt by his last three games when he has averaged just 5.3 points. --Field Level Media Our Standards: The Thomson Reuters Trust Principles. , opens new tab

AAR to announce second quarter fiscal year 2025 results on January 7, 2025The India women's national cricket team will lock horns against the host Australia women's national cricket team in the crucial second ODI of the three-match series. The IND-W vs AUS-W 2nd ODI 2024 will be hosted in Brisbane. The crucial encounter between the two sides will start at 5:15 AM IST (Indian Standard Time). The live telecast of the IND-W vs AUS-W ODI series will be available on Star Sports 1 and Star Sports 2 TV channels. Fans in India will be able to watch the live streaming of the India Women vs Australia Women ODI Series on Disney+ Hotstar but at the cost of a subscription fee. IND-W vs AUS-W 2nd ODI 2024, Brisbane Weather, Rain Forecast and Pitch Report: Here’s How Weather Will Behave for India Women vs Australia Women at Allan Border Field . IND-W vs AUS-W 2nd ODI 2024 Gearing Up For 2nd ODI 👌👌 🆚 Australia 📆 Sunday, 8th December ⏰ 5:15 AM IST 💻📱 https://t.co/oYTlePud07 #TeamIndia | #AUSvIND pic.twitter.com/FCyyrZG6lM — BCCI Women (@BCCIWomen) December 7, 2024 (SocialLY brings you all the latest breaking news, viral trends and information from social media world, including Twitter, Instagram and Youtube. The above post is embeded directly from the user's social media account and LatestLY Staff may not have modified or edited the content body. The views and facts appearing in the social media post do not reflect the opinions of LatestLY, also LatestLY does not assume any responsibility or liability for the same.)US announces nearly $1-B in new military aid for Ukraine